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Can you provide evidence that each Amplify ingredient extends lifespan and/or improves healthspan in animal models?Updated 2 months ago


  • Dang et al. Berberine ameliorates cellular senescence and extends the lifespan of mice via regulating p16 and cyclin protein expression. Aging Cell 2020.
  • Yu et al. Berberine Improves Cognitive Deficiency and Muscular Dysfunction via Activation of the AMPK/SIRT1/PGC-1a Pathway in Skeletal Muscle from Naturally Aging Rats. The Journal of Nutrition, Health, & Aging 2018;
  • Durairajan et al. Berberine ameliorates β-amyloid pathology, gliosis, and cognitive impairment in an Alzheimer's disease transgenic mouse model. Neurobiology of Aging 2012;


Urolithin A:

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