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Can you provide evidence that each Amplify ingredient extends lifespan and/or improves healthspan in animal models?Updated 15 days ago

Berberine:

Glycine:

  • Miller et al. Glycine supplementation extends lifespan of male and female mice. Aging Cell 2019; https://doi.org/10.1111/acel.12953

  • Brind et al. Dietary glycine supplementation mimics lifespan extension by dietary methionine restriction in Fisher 344 rats. The FASEB Journal 2011; https://doi.org/10.1096/fasebj.25.1_supplement.528.2

  • Chen et al. Dietary Supplementation with Glycine Enhances Intestinal Mucosal Integrity and Ameliorates Inflammation in C57BL/6J Mice with High-Fat Diet-Induced Obesity. The Journal of Nutrition 2021; https://doi.org/10.1093/jn/nxab058

  • Ullah et al. Glycine, the smallest amino acid, confers neuroprotection against D-galactose-induced neurodegeneration and memory impairment by regulating c-Jun N-terminal kinase in the mouse brain. Journal of Neuroinflammation 2020; https://doi.org/10.1186/s12974-020-01989-w

Coenzyme Q10:

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